I've been reading about HP Lovecraft and his Cthlulu mythos, and it seems that most of his stories deal with the infinite levels of knowledge and man trying to make sense of them

"When such vistas are opened, the mind of the protagonist-investigator is often destroyed. Those who actually encounter "living" manifestations of the incomprehensible are particularly likely to go mad, as is the case of the titular character in The Music of Erich Zann. The story features an insane mute violist virtuoso's sixth-floor apartment, whose window is the only one high enough to see over a wall on a mysterious, disappearing Parisian street—a wall whose other side contains unexplainable horrors" - wikipedia

does this not sound like the warp or what, humans trying to use the warp for their own ends and it drives them mad or some demon eats there brain